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[无锡-滨湖区]上海药明合联生物技术有限公司
职位:精英计划-研发-蛋白质质谱方向(MJ010915)
发布时间:2026-10-30
工作地点:其它
信息来源:前程无忧(51JOB)
职位类型:全职
专业标签:生物科学
职位描述
专业1:基础医学类
职能类别:生物工程/生物制药
SUMMARY AND KEY ACCOUNTIBILITIES:
Wuxi process development analytical science team is seeking a
skilled and highly motivated candidate to fill a Sr. Scientist to director
level position (depending on candidate’s experience) in Wuxi. This position will
work collaboratively in cross-functional teams on a range of programs. The
candidate will work in a highly collaborative environment to utilize skills in
partnership with internal and external experts.
l Lead a team of scientists in analytical science team to
support in a broad range of biologic projects
l Oversee all aspects of structural characterization work of
protein therapeutics, including but not limited to SEC, IEX, titer, CE-SDS,
icIEF, mass spectrometry
l Develop and implement novel LC-MS based analytical methods to
support in-depth characterization of biologics and other new modalities (AAV,
mRNA, oligonucleotide etc), including but not limited to intact mass, cIEF-MS,
peptide mapping, disulfide mapping and glycan analysis
Support technical transfer, training and trouble-shooting of
protein production for CMC development purposes
REQUIREMENTS:
You love analytics and are passionate about using data to drive
key business decisions. You love learning new technological skills and working
through collaboration. You will provide expertise in the field of in-depth
protein analysis as it pertains to biologics characterization and other novel
therapy related work with possibility to support other modalities as
opportunities arise.
l Direct expertise in protein characterization or in mass
spec-based proteomics (DDA, MRM, PRM et al.) is required. Previous experience
in protein characterization of biologics and/or glycoproteins using peptide
mapping, intact protein analysis is preferred.
l In-depth knowledge and hands-on experience in different types
of analytical separation techniques and data processing analyses with focus on
mass spectrometry applications.
l Knowledge of other analytical techniques such as
chromatography (HPLC/UPLC), electrophoresis (CE-SDS, icIEF), biophysical
methods and DNA analysis
l Broad expertise and familiarity with protein and antibody
production and CMC development
l Thorough understanding of biochemistry and structural biology
l Strong problem-solving and troubleshooting skills,
capabilities in experimental design and execution, ability to work on multiple
projects simultaneously, as well ability to work independently and collaborate
cross-functionally
EDUCATION (Indicate the mini. requirement & preferred discipline):
l Ph.D.
Major:Analytical
chemistry/ Biochemistry/Biophysics/Protein Chemistry, or related field
OTHER SKILLS, ABILITIES & EXPERIENCE:
l Good communication skills required, speaks fluent English
Strong team-working spirit
公司简要介绍:
公司名称:上海药明合联生物技术有限公司
公司类型:外资(欧美)
公司规模:1000-5000人
公司介绍:药明合联(WuXi XDC)是由药明生物和合全药业联合成立的合资公司,是全球领先的开放式、一体化生物偶联制药能力和技术赋能平台。公司为全球生物偶联制药公司和生物偶联药开发者们提供全方位的端到端CRDMO服务,实现从概念到商业化生产的全过程整合,并通过高度集成ADC工艺研发和生产的供应链,加速并变革全球生物偶联药研发进程,为客户提供开放式,一体化的偶联制药技术平台,降低研发成本,造福病患。 药明合联主要由三个业务部门组成,上海生物偶联研发部负责偶联药物的早期研究和工艺开发,无锡高新区的生物偶联药园区负责偶联药物的GMP偶联生产,成品制剂及工艺开发和制剂生产,常州小分子基地承担载荷和连接子的研发和生产。
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